SGK1-IN-3 (hydrochloride)
SGK1-IN-3 hydrochloride (compound 3a) is a potent SGK1 inhibitor with an IC50 of [1].
Product Specifications
UNSPSC
12352005
Target
SGK
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sgk1-in-3-hydrochloride.html
Purity
96.65
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C2=CC=C(C=C2)NS(=O)(C3=C(C(Cl)=CC=C3)Cl)=O)=NC4=C1C=NN4)N[C@@H]5CCNC5.[H]Cl
Molecular Formula
C23H21Cl3N6O3S
Molecular Weight
567.88
References & Citations
[1]Halland N, et al. Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis. J Med Chem. 2022;65 (2) :1567-1584.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4988907 1.0 µg DNA
Fam160b1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
Sign In for Pricing
View Details EIA06164Bo 1 Kit
Bovine platelet-associated Complement 3 (PAC3) ELISA Kit
Sign In for Pricing
View Details MR221174L4V 200 µL
Wbscr28 (Tmem270) (NM_194065) Mouse Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details bsm-63009R-BF647 100 µL
UBF1 Recombinant Antibody, AbBy Fluor™ 647 Conjugated
Sign In for Pricing
View Details