SGK1-IN-3 (hydrochloride)
SGK1-IN-3 hydrochloride (compound 3a) is a potent SGK1 inhibitor with an IC50 of [1].
Product Specifications
UNSPSC
12352005
Target
SGK
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sgk1-in-3-hydrochloride.html
Purity
96.65
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C2=CC=C(C=C2)NS(=O)(C3=C(C(Cl)=CC=C3)Cl)=O)=NC4=C1C=NN4)N[C@@H]5CCNC5.[H]Cl
Molecular Formula
C23H21Cl3N6O3S
Molecular Weight
567.88
References & Citations
[1]Halland N, et al. Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis. J Med Chem. 2022;65 (2) :1567-1584.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MR216356L4 10 µg
Krtap19 (Krtap19-9b) (NM_133359) Mouse Tagged Lenti ORF Clone
Sign In for Pricing
View Details 
NBP2-12228R 0.1 mL
Rat Monoclonal GRO2 Antibody (RM0209-13N6) [DyLight 550]
Sign In for Pricing
View Details 
P4214-32B 50 µg
Plectin (PLTN, PCN, Hemidesmosomal Protein 1, HD1, PLEC1) discontinued
Sign In for Pricing
View Details