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SGK1-IN-3 (hydrochloride)

SGK1-IN-3 hydrochloride (compound 3a) is a potent SGK1 inhibitor with an IC50 of [1].

Product Specifications

UNSPSC

12352005

Target

SGK

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sgk1-in-3-hydrochloride.html

Purity

96.65

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(C2=CC=C(C=C2)NS(=O)(C3=C(C(Cl)=CC=C3)Cl)=O)=NC4=C1C=NN4)N[C@@H]5CCNC5.[H]Cl

Molecular Formula

C23H21Cl3N6O3S

Molecular Weight

567.88

References & Citations

[1]Halland N, et al. Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis. J Med Chem. 2022;65 (2) :1567-1584.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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