DTE

DTE (Dithioerythritol) is a sulfur-containing sugar derived from the corresponding 4-carbon monosaccharide erythrose. DTE is an epimer of Dithiothreitol (DTT) (HY-15917) . DTE is a thiol reducing agent[1].

Product Specifications

CAS Number

[6892-68-8]

Product Name Alternative

Dithioerythritol; Cleland’s reagent

UNSPSC

12352200

Hazard Statement

H302, H412

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/DTE.html

Purity

99.69

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

O[C@H]([C@H](O)CS)CS

Molecular Formula

C4H10O2S2

Molecular Weight

154.25

Precautions

H302, H412

References & Citations

[1]Lo S, et al., Dithioerythritol (DTE) prevents inhibitory effects of triphenyltin (TPT) on the key enzymes of the human sex steroid hormone metabolism. J Steroid Biochem Mol Biol. 2003 Apr;84 (5) :569-76.|[2]Bucak MN, et al., Effects of curcumin and dithioerythritol on frozen-thawed bovine semen. Andrologia. 2012 May;44 Suppl 1:102-9.|[3]Heidari R, et al., Dithiothreitol supplementation mitigates hepatic and renal injury in bile duct ligated mice: Potential application in the treatment of cholestasis-associated complications. Biomed Pharmacother. 2018 Mar;99:1022-1032.