Klotho-derived peptide 1
Klotho-derived peptide 1 (KP1 human) blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model[1].
Product Specifications
Product Name Alternative
KP1 (human)
UNSPSC
12352209
Target
P38 MAPK; TGF-beta/Smad
Type
Peptides
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt; TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/klotho-derived-peptide-1.html
Smiles
Molecular Formula
C149H203N39O43
Molecular Weight
3228.44
References & Citations
[1]Yuan Q, et al., A Klotho-derived peptide protects against kidney fibrosis by targeting TGF-β signaling. Nat Commun. 2022 Jan 21;13 (1) :438.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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