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Tivoxavir marboxil

AV5124, a prodrug of AV5116, is an orally active influenza virus cap-dependent endonuclease (CEN) endonuclease inhibitor[1].

Product Specifications

CAS Number

2417851-93-3

Product Name Alternative

AV5124

UNSPSC

12352005

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/av5124.html

Purity

99.55

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

COC(OCOC1=C2N(C=CC1=O)N([C@H]3C4=CC=C(F)C(F)=C4CSC5=C3SC=C5)[C@@]6([H])N(CCOC6)C2=O)=O

Molecular Formula

C25H21F2N3O7S2

Molecular Weight

577.58

References & Citations

[1]Andrei A Ivashchenko, et al. Synthesis, inhibitory activity and oral dosing formulation of AV5124, the structural analogue of influenza virus endonuclease inhibitor baloxavir. J Antimicrob Chemother. 2021 Mar 12;76 (4) :1010-1018.

Shipping Conditions

Room Temperature

Storage Conditions

RT, sealed storage, away from moisture and light

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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