Tivoxavir marboxil
AV5124, a prodrug of AV5116, is an orally active influenza virus cap-dependent endonuclease (CEN) endonuclease inhibitor[1].
Product Specifications
CAS Number
[2417851-93-3]
Product Name Alternative
AV5124
UNSPSC
12352005
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/av5124.html
Purity
99.55
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
COC(OCOC1=C2N(C=CC1=O)N([C@H]3C4=CC=C(F)C(F)=C4CSC5=C3SC=C5)[C@@]6([H])N(CCOC6)C2=O)=O
Molecular Formula
C25H21F2N3O7S2
Molecular Weight
577.58
References & Citations
[1]Andrei A Ivashchenko, et al. Synthesis, inhibitory activity and oral dosing formulation of AV5124, the structural analogue of influenza virus endonuclease inhibitor baloxavir. J Antimicrob Chemother. 2021 Mar 12;76 (4) :1010-1018.
Shipping Conditions
Room Temperature
Storage Conditions
RT, sealed storage, away from moisture and light
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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