Gly-7-MAD-MDCPT
Gly-7-MAD-MDCPT (compound 4b) is an anticancer agent. Gly-7-MAD-MDCPT is a Camptothecin (HY-16560) compound, it shows cytotoxicity to various cancer cells with IC50 values of 10-1000 nM[1].
Product Specifications
CAS Number
[2378427-68-8]
UNSPSC
12352005
Target
ADC Payload; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gly-7-mad-mdcpt.html
Purity
95.15
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
NCC(NCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(OCO6)=C6C=C51)=O
Molecular Formula
C24H22N4O7
Molecular Weight
478.45
References & Citations
[1]Jeffrey Scott, et al. Preparation of camptothecin peptide conjugates as antitumor agents. WO2019195665. 2019 10-10.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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