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Gly-7-MAD-MDCPT

Product Specifications

UNSPSC Description

Gly-7-MAD-MDCPT (compound 4b) is an anticancer agent. Gly-7-MAD-MDCPT is a Camptothecin (HY-16560) compound, it shows cytotoxicity to various cancer cells with IC50 values of 10-1000 nM[1].

Target Antigen

ADC Cytotoxin; Topoisomerase

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gly-7-mad-mdcpt.html

Purity

95.15

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

NCC(NCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(OCO6)=C6C=C51)=O

Molecular Weight

478.45

References & Citations

[1]Jeffrey Scott, et al. Preparation of camptothecin peptide conjugates as antitumor agents. WO2019195665. 2019 10-10.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-132164/Gly-7-MAD-MDCPT-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-132164/Gly-7-MAD-MDCPT-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2378427-68-8

Available Sizes

Curated Selection

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