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KRAS G12D inhibitor 3 (TFA)

Selected Variant

HY-115880A-01

Size: 5 mg

KRAS G12D inhibitor 3 TFA is a KRAS G12D inhibitor with an IC50 of [1]. KRAS G12D inhibitor 3 (TFA) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

2757095-12-6

Product Name Alternative

CA-074Me

UNSPSC

12352005

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kras-g12d-inhibitor-3-tfa.html

Purity

98.18

Solubility

DMSO : ≥ 100 mg/mL

Smiles

C#CC1=C(C=CC2=C1C(C3=C(C4=C(C(N5CC6CCC(N6)C5)=NC(OC[C@@]78CCCN7C[C@@H](C8)F)=N4)C=C3Cl)F)=CC(O)=C2)F.OC(C(F)(F)F)=O

Molecular Formula

C36H32ClF6N5O4

Molecular Weight

748.11

References & Citations

[1]Xing DAI, et al. Quinazoline compounds, preparation methods and uses thereof. WO2022002102A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

K-Ras

Available Sizes

Price

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