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Cianergoline

Cianergoline is a ergoline derivative with the activity of reducing intraocular pressure (IOP) . Its primary regulatory mechanism involves the inhibition of sympathetic nervous function, achieved through actions on both prejunctional (DA2) and postjunctional (α1) adrenergic receptors. Cianergoline can be used for research in the field of glaucoma[1].

Product Specifications

CAS Number

74627-35-3

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/cianergoline.html

Smiles

CN1[C@@](C2)([H])[C@@](C[C@@H](CC(C#N)C(N)=O)C1)([H])C3=C4C2=CNC4=CC=C3

Molecular Formula

C19H22N4O

Molecular Weight

322.40

References & Citations

[1]POTTER D E, et al. Cianergoline lowers intraocular pressure in rabbits and monkeys and inhibits contraction of the cat nictitans by suppressing sympathetic neuronal function[J]. Journal of Ocular Pharmacology and Therapeutics, 1987, 3 (4) : 309-321.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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