Recombinant Human Myelin Oligodendrocyte Glycoprotein
Recombinant Human Myelin Oligodendrocyte Glycoprotein
Product Specifications
Product Name Alternative
MOG
Gene Name
MOG
UniProt
Q16653
Cellular Locus
[Isoform 1]: Cell membrane , Multi-pass membrane protein , Multi-pass membrane protein , Single-pass type I membrane protein , Single-pass type I membrane protein , Single-pass type I membrane protein , Single-pass type I membrane protein , Single-pass type I membrane protein , Single-pass type I membrane protein , Single-pass type I membrane protein
Reactivity
Human
Target Antigen
Myelin-oligodendrocyte glycoprotein
Target
Myelin Oligodendrocyte Glycoprotein
Type
Protein
Applications
WB
Dilution
Reconstitute lyophilized MOG in sterile 10mM acetic acid to no less than 100ug/ml which can be further diluted in other aqueous solutions as needed.
Form
Lyophilized
Function
Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. {PubMed:21880773}.
Storage Conditions
Although stable at room temperature for 3 weeks, the lyophilized product is best stored at or below -20°C. Upon reconstitution, product can be stored at 4°C for up to 1 week but is best stored at or below -20°C for longer periods of time. Addition of a carrier protein (such as 0.1% HSA or BSA) is recommended for long- term storage.
Product Datasheet
https://www.qedbio.com/wp-content/uploads/pdf/24202P.pdf
Specificity
Myelin Oligodendrocyte Glycoprotein
Formulation
Reconstitute lyophilized MOG in sterile 50mM acetic acid to no less than 100ug/ml which can be further diluted in other aqueous solutions as needed.
Target Background
Myelin Oligodendrocyte Glycoprotein (MOG) is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Given its localization, it is a prime target antigen of immune-mediated demyelination. MOG is involved in completion and maintenance of the myelin sheath and in cell-cell communication. MOG is differentially expressed in the dorsolateral prefrontal cortex and in the temporal lobe from patients with schizophrenia.
CAS Number
9000-83-3
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