5-Chloroisoquinoline
5-Chloroisoquinoline (compound 42) is an inhibitor of SARM1 (Sterile alpha and toll/interleukin receptor (TIR) motif containing protein 1), an enzyme involved in axon degeneration that catalyzes multiple activities through a ternary complex mechanism. 5-Chloroisoquinoline can be used in the study of neurodegenerative diseases or axon degeneration[1].
Product Specifications
CAS Number
[5430-45-5]
UNSPSC
12352005
Hazard Statement
H301, H318
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-chloroisoquinoline.html
Purity
98.0
Smiles
ClC1=CC=CC2=CN=CC=C21
Molecular Formula
C9H6ClN
Molecular Weight
163.60
Precautions
H301, H318
References & Citations
[1]Inhibitors of SARM1. World Intellectual Property Organization, WO2019236879 A1 2019-12-12.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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