What is the catalog number for Morin?

The catalog number for Morin is HY-N0621.

What sizes are available for Morin?

Morin is available in the following size(s): 1 mg, 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Morin come in?

Morin is available in 7 different pack sizes.

Morin is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Morin?

Morin is manufactured by QuantiMol.

What is the estimated delivery time for Morin?

Estimated delivery time for Morin is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Morin?

The safety data sheet for Morin is available here: http://file.medchemexpress.com/batch_PDF/HY-N0621/Morin-SDS-MedChemExpress.pdf.

Morin

Morin is an orally active plant-derived flavonoid. Morin inhibits ROS generation. Morin induces Apoptosis. Morin inhibits PTP1B (IC50 of 15 μM) and activates the insulin receptor. Morin has a detoxifying effect. Morin can be used in diabetes, leukemia, colon cancer, cervical cancer, Parkinson's disease and hypertension research[1][2][3][4][5][6][7][8][9][10][11][12].

Product Specifications

CAS Number

480-16-0

UNSPSC

12352005

Hazard Statement

H411

Target

Apoptosis; Insulin Receptor; Phosphatase; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Protein Tyrosine Kinase/RTK

Applications

Cancer-programmed cell death

Field of Research

Cancer; Metabolic Disease; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/morin.html

Purity

98.11

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C1C(O)=C(C2=CC=C(O)C=C2O)OC3=CC(O)=CC(O)=C13

Molecular Formula

C15H10O7

Molecular Weight

302.24

Precautions

H411

References & Citations

[1]Duthie G, et al. Antioxidant capacity of flavonoids in hepatic microsomes is not reflected by antioxidant effects in vivo. Oxid Med Cell Longev. 2012;2012:165127.|[2]Lian HZ, et al. Morin applied in speciation of aluminium in natural waters and biological samples by reversed-phase high-performance liquid chromatography with fluorescence detection. Anal Bioanal Chem. 2003 Jun;376 (4) :542-8. Epub 2003 May 9.|[3]Zhang R, et al. Cellular protection of morin against the oxidative stress induced by hydrogen peroxide. Chem Biol Interact. 2009 Jan 15;177 (1) :21-7.|[4]Kuo HM, et al. Morin inhibits the growth of human leukemia HL-60 cells via cell cycle arrest and induction of apoptosis through mitochondria dependent pathway. Anticancer Res. 2007 Jan-Feb;27 (1A) :395-405.|[5]Paoli P, et al. The insulin-mimetic effect of Morin: a promising molecule in diabetes treatment. Biochim Biophys Acta. 2013 Apr;1830 (4) :3102-11.|[6]Zhang Q, et al. Molecular mechanism of anti-cancerous potential of Morin extracted from mulberry in Hela cells. Food Chem Toxicol. 2018 Feb;112:466-475. |[7]Zhang ZT, et al. Morin exerts neuroprotective actions in Parkinson disease models in vitro and in vivo. Acta Pharmacol Sin. 2010 Aug;31 (8) :900-6.|[8]Parihar VK, et al. Anticlastogenic activity of morin against whole body gamma irradiation in Swiss albino mice. Eur J Pharmacol. 2007 Feb 14;557 (1) :58-65.|[9]Merwid-Ląd A, et al. The effects of morin, a naturally occurring flavonoid, on cyclophosphamide-induced toxicity in rats. Advances in Clinical and Experimental Medicine, 2011, 20 (6) : 683-690. |[10]Prahalathan P, et al. Effect of morin, a flavonoid against DOCA-salt hypertensive rats: a dose dependent study. Asian Pac J Trop Biomed. 2012 Jun;2 (6) :443-8. |[11]Kuzu M, et al. Morin attenuates doxorubicin-induced heart and brain damage by reducing oxidative stress, inflammation and apoptosis. Biomed Pharmacother. 2018 Oct;106:443-453.|[12]Sreedharan V, et al. Effect of morin on tissue lipid peroxidation and antioxidant status in 1, 2-dimethylhydrazine induced experimental colon carcinogenesis. Invest New Drugs. 2009 Feb;27 (1) :21-30.