Cardol triene

Cardol triene is a phenol found in cashew nut shell liquid that competitively and irreversibly inhibits mushroom tyrosinase (IC50=22.5 μM) . It is schistosomicidal, killing 25, 75, and 100% of S. mansoni worms after 24 hours when used at concentrations of 50, 100, or 200 μM, respectively. It has been used as a starting material for the synthesis of bis-benzoxazines.

Product Specifications

CAS Number

[79473-24-8]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cardol-triene.html

Smiles

OC1=CC(CCCCCCC/C=C\C/C=C\CC=C)=CC(O)=C1

Molecular Formula

C21H30O2

Molecular Weight

314.46

References & Citations

[1]Alvarenga, et al. Schistosomicidal activity of alkyl-phenols from the cashew Anacardium occidentale against Schistosoma mansoni adult worms. J. Agric. Food Chem. 64 (46), 8821-8827 (2016) .