ZINC00640089
ZINC00640089 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00640089 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00640089 has good potential for research in inflammatory breast cancer (IBC) [1].
Product Specifications
CAS Number
[667880-11-7]
UNSPSC
12352005
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zinc00640089.html
Purity
99.95
Solubility
DMSO : 8 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(CN1C(C2=C3C1=CC=CC3=CC=C2)=O)NC4=C(C(F)(F)F)C=CC=C4
Molecular Formula
C20H13F3N2O2
Molecular Weight
370.33
References & Citations
[1]Santiago-Sánchez GS, et al. Targeting Lipocalin-2 in Inflammatory Breast Cancer Cells with Small Interference RNA and Small Molecule Inhibitors. Int J Mol Sci. 2021 Aug 10;22 (16) :8581.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Dedicated for Diverse Library
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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