IFN-gamma R1/CD119, Mouse (HEK293, Fc)
Selected Variant
HY-P73133
Size: 1 Each
IFN-gamma R1 (CD119), one of the subunit of IFN-gamma receptor, is a receptor for IFN-gamma. IFN-gamma R1 forms the functional receptor with IFN-gamma R2. Upon binding with IFN-gamma, IFN-gamma R1 and IFN-gamma R2 oligomerize and transphosphorylate[1]. Then, JAK1 and JAK2 are phosphorylated and activated, and STAT1 is recruited to the receptor complex. Phosphorylated STAT1 translocates to the nucleus, where it regulates the expression of IFN-responsive genes (e.g. CD54) [2]. IFN-gamma R1/CD119 Protein, Mouse (HEK293, Fc) is a recombinant mouse IFN-gamma R1 (A26-D253) with C-terminal hFc tag, which is produced in HEK293 cells.
Product Specifications
Product Name Alternative
IFN-gamma R1/CD119 Protein, Mouse (HEK293, Fc), Mouse, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/ifn-gamma-r1-cd119-protein-mouse-hek293-fc.html
Molecular Formula
15979 (Gene_ID) P15261 (A26-D253) (Accession)
Molecular Weight
Approximately 70-75 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
References & Citations
Shipping Conditions
Dry ice.
Scientific Category
Recombinant Proteins
Price
Frequently Asked Questions
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