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(3β,7β,12β,20Z) -3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid

Selected Variant

HY-N8090

Size: 1 mg

(3β,7β,12β,20Z) -3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid, a lanostane triterpenoids, exhibits obvious NO inhibitory activity on n LPS-induced BV-2 microglia cells with an IC50 of 9.55 uM. (3β,7β,12β,20Z) -3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid has anti-inflammatory activities[1].

Product Specifications

CAS Number

1961358-02-0

UNSPSC

12352211

Target

NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/3β-7β-12β-20z-3-7-12-trihydroxy-11-15-23-trioxo-lanost-8-20-dien-26-oic-acid.html

Purity

97.84

Solubility

10 mM in DMSO

Smiles

C[C@]([C@@]([C@H]1/C(C)=C\C(CC(C)C(O)=O)=O)([C@@H]2O)C)(C(C1)=O)C([C@H](C[C@@]3([H])C4(C)C)O)=C(C2=O)[C@]3(CC[C@@H]4O)C

Molecular Formula

C30H42O8

Molecular Weight

530.65

References & Citations

[1]Yang Jiao, et al. Lanostane triterpenoids from Ganoderma curtisii and their NO production inhibitory activities of LPS-induced microglia. Bioorg Med Chem Lett. 2016 Aug 1;26 (15) :3556-61.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Price

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