Meticrane

Meticrane is a diuretic. Meticrane inhibits the reabsorption of sodium and chloride ions in the distal convoluted tubule. Meticrane is used to treat essential hypertension.

Product Specifications

CAS Number

[1084-65-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Chloride Channel; Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Meticrane.html

Purity

98.93

Solubility

DMSO : ≥ 50 mg/mL|H2O : < 0.1 mg/mL

Smiles

O=S(C1=C(C)C=C(C2=C1)CCCS2(=O)=O)(N)=O

Molecular Formula

C10H13NO4S2

Molecular Weight

275.34

Precautions

H302, H315, H319, H335

References & Citations

[1]Rumiko TANAKA, et al. Crystal Structure of Meticrane. ANALYTICAL SCIENCES 2007, VOL. 23.|[2]Lesterhuis WJ, et al. Network analysis of immunotherapy-induced regressing tumours identifies novel synergisticdrug combinations. Sci Rep. 2015 Jul 21;5:12298.