5-Formylcytosine
5-Formylcytosine is a modified base, which is oxidized from 5-methylcytosine. 5-Formylcytosine is a intermediate of in the active DNA demethylation[1].
Product Specifications
CAS Number
4425-59-6
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-formylcytosine.html
Purity
96.4
Smiles
O=CC1=C(NC(N=C1)=O)N
Molecular Formula
C5H5N3O2
Molecular Weight
139.11
Precautions
H315, H319
References & Citations
[1]Maiti A, et al., Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites. J Biol Chem. 2011 Oct 14;286 (41) :35334-35338.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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