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5-Formylcytosine

5-Formylcytosine is a modified base, which is oxidized from 5-methylcytosine. 5-Formylcytosine is a intermediate of in the active DNA demethylation[1].

Product Specifications

CAS Number

[4425-59-6]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-formylcytosine.html

Purity

96.4

Smiles

O=CC1=C(NC(N=C1)=O)N

Molecular Formula

C5H5N3O2

Molecular Weight

139.11

Precautions

H315, H319

References & Citations

[1]Maiti A, et al., Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites. J Biol Chem. 2011 Oct 14;286 (41) :35334-35338.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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