Histone H2A.X (Phospho Tyr142) rabbit pAb
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],
Product Specifications
Background
Synonyms
H2AFX; H2AX; Histone H2A.x; H2a/x
Gene ID
3014
UniProt
P16104
Cellular Locus
Nucleus. Chromosome.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic Peptide of Histone H2A.X (Phospho Tyr142)
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Dilution
WB: 1:1000-2000
Molecular Weight
15kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES20578-1.pdf
Observed Molecular Weight
15 kD
Subcellular Location
Nucleus . Chromosome .
Other Product Names
H2AFX; H2AX; Histone H2A.x; H2a/x
Gene ID (Human)
3014
SwissProt (Human)
P16104
Available Sizes
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