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A-39355

A-39355 is a compound that can overcome multidrug resistance and has the activity of reversing multidrug resistance. A-39355 can enhance the cytotoxicity of antitumor compounds in multidrug-resistant cells, increase the accumulation of compounds in cells, inhibit the efflux of compounds, and compared with calcium antagonists, it has no serious hypotensive effect. Its activity may be unrelated to the ability to block calcium transport.

Product Specifications

CAS Number

144092-66-0

UNSPSC

12352005

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/a-39355.html

Smiles

COC1=C(N2CCN(CCCN3C4=C(C5=C3CCCCCC5)C=CC=C4)CC2)C=CC=C1.Cl.Cl

Molecular Formula

C28H39Cl2N3O

Molecular Weight

504.53

References & Citations

[1]Reversal of multidrug resistance by two novel indole derivatives

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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