A-39355
A-39355 is a compound that can overcome multidrug resistance and has the activity of reversing multidrug resistance. A-39355 can enhance the cytotoxicity of antitumor compounds in multidrug-resistant cells, increase the accumulation of compounds in cells, inhibit the efflux of compounds, and compared with calcium antagonists, it has no serious hypotensive effect. Its activity may be unrelated to the ability to block calcium transport.
Product Specifications
CAS Number
144092-66-0
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/a-39355.html
Smiles
COC1=C(N2CCN(CCCN3C4=C(C5=C3CCCCCC5)C=CC=C4)CC2)C=CC=C1.Cl.Cl
Molecular Formula
C28H39Cl2N3O
Molecular Weight
504.53
References & Citations
[1]Reversal of multidrug resistance by two novel indole derivatives
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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