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PPARα/γ agonist 5

PPARα/γ agonist 5 is a dual PPARα/γ agonist with significant biological activity exhibited at low concentrations. The EC50 of PPARα/γ agonist 5 are 0.358μM and 1.21μM respectively, showing its potential in inhibiting type 2 diabetes and lipid metabolism disorders. PPARα/γ agonist 5 was selected for clinical development due to its high efficacy[1].

Product Specifications

CAS Number

849150-59-0

UNSPSC

12352005

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/pparα-γ-agonist-5.html

Smiles

OC([C@H](OC)CC1=C2C(C=CS2)=C(C=C1)OCCC3=C(C)OC(C4=CC=CC=C4)=N3)=O

Molecular Formula

C24H23NO5S

Molecular Weight

437.51

References & Citations

[1]Aleglitazar, a new, potent, and balanced dual PPARa/c agonist for the treatment of type II diabetes

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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