PPARα/γ agonist 5
PPARα/γ agonist 5 is a dual PPARα/γ agonist with significant biological activity exhibited at low concentrations. The EC50 of PPARα/γ agonist 5 are 0.358μM and 1.21μM respectively, showing its potential in inhibiting type 2 diabetes and lipid metabolism disorders. PPARα/γ agonist 5 was selected for clinical development due to its high efficacy[1].
Product Specifications
CAS Number
849150-59-0
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pparα-γ-agonist-5.html
Smiles
OC([C@H](OC)CC1=C2C(C=CS2)=C(C=C1)OCCC3=C(C)OC(C4=CC=CC=C4)=N3)=O
Molecular Formula
C24H23NO5S
Molecular Weight
437.51
References & Citations
[1]Aleglitazar, a new, potent, and balanced dual PPARa/c agonist for the treatment of type II diabetes
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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