(R) -Fluoxetine (hydrochloride)
(R) -Fluoxetine hydrochloride, an antidepressant, is serotonin reuptake inhibitor (SSRI) . (R) -Fluoxetine hydrochloride has modest affinity at the 5-HT2A and 5-HT2C receptors[1][2].
Product Specifications
CAS Number
[114247-09-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H318
Target
Serotonin Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/r-fluoxetine-hydrochloride.html
Purity
99.82
Solubility
H2O : ≥ 50 mg/mL
Smiles
FC(C1=CC=C(O[C@@H](C2=CC=CC=C2)CCNC)C=C1)(F)F.[H]Cl
Molecular Formula
C17H19ClF3NO
Molecular Weight
345.79
Precautions
H302, H315, H318
References & Citations
[1]Henry ME, et al. A comparison of brain and serum pharmacokinetics of R-fluoxetine and racemic fluoxetine: A 19-F MRS study. Neuropsychopharmacology. 2005;30 (8) :1576-1583.|[2]Marwari S, et al. (R) -fluoxetine enhances cognitive flexibility and hippocampal cell proliferation in mice. J Psychopharmacol. 2018;32 (4) :441-457.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
Available Sizes
Curated Selection
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