NF-κΒ activator 1
Product Specifications
UNSPSC Description
NF-κΒ activator 1 (compound 32) is a potent NF-κΒ activator with an EC50 of 0.9 μM. NF-κΒ activator 1 induces superoxide dismutase (SOD)2 mRNA expression[1].
Target Antigen
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nf-κ-activator-1.html
Smiles
O=C(O)C1=CC=CC(C2=CSC(NC3=CC=CC=C3F)=N2)=C1
Molecular Weight
314.33
References & Citations
[1]Mathew B, et al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-ҡB activators for the treatment of ALS [published online ahead of print, 2020 Oct 22]. Eur J Med Chem. 2020;112952.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-134476/NF-κ-activator-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-134476/NF-κ-activator-1-SDS-MedChemExpress.pdf
CAS Number
2387524-59-4
Available Sizes
Curated Selection
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