Dentonin

Dentonin (AC-100) is a synthetic fragment derived from MEPE. Dentonin enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin has no significant effect to mature osteoblasts. Dentonin can be used for the research of phosphate homeostasis and bone metabolism[1].

Product Specifications

CAS Number

[400090-20-2]

Product Name Alternative

AC-100

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/dentonin.html

Purity

98.63

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1N(CCC1)C([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H](CC(O)=O)NC([C@H](CC(N)=O)NC([C@H](CC(O)=O)NC(CNC([C@H](CCCNC(N)=N)NC([C@H](CCC(O)=O)NC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@@H](N)[C@H](O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CO)C(NCC(N[C@@H](CC(O)=O)C(NCC(N[C@@H](CCC(N)=O)C(N3[C@@H](CCC3)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)CC(O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C107H160N30O42

Molecular Weight

2538.59

References & Citations

[1]Andrew P Sprowson, et al. ASARM-truncated MEPE and AC-100 enhance osteogenesis by promoting osteoprogenitor adhesion. J Orthop Res. 2008 Sep;26 (9) :1256-62.|[2]N Six, et al. Dentonin, a MEPE fragment, initiates pulp-healing response to injury.J Dent Res. 2007 Aug;86 (8) :780-5.