Dentonin
Product Specifications
UNSPSC Description
Dentonin (AC-100) is a synthetic fragment derived from MEPE. Dentonin enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin has no significant effect to mature osteoblasts. Dentonin can be used for the research of phosphate homeostasis and bone metabolism[1].
Target Antigen
Others
Type
Peptides
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/dentonin.html
Purity
98.63
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(CCC1)C([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H](CC(O)=O)NC([C@H](CC(N)=O)NC([C@H](CC(O)=O)NC(CNC([C@H](CCCNC(N)=N)NC([C@H](CCC(O)=O)NC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@@H](N)[C@H](O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CO)C(NCC(N[C@@H](CC(O)=O)C(NCC(N[C@@H](CCC(N)=O)C(N3[C@@H](CCC3)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)CC(O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O
Molecular Weight
2538.59
References & Citations
[1]Andrew P Sprowson, et al. ASARM-truncated MEPE and AC-100 enhance osteogenesis by promoting osteoprogenitor adhesion. J Orthop Res. 2008 Sep;26(9):1256-62.|[2]N Six, et al. Dentonin, a MEPE fragment, initiates pulp-healing response to injury.J Dent Res. 2007 Aug;86(8):780-5.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P2633/Dentonin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P2633/Dentonin-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
400090-20-2
Available Sizes
Curated Selection
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