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Follistatin/FST, Human (HEK293, His)

Follistatin (FST) is a regulator of TGFβ family signaling and acts by selectively binding to TGFβ family ligands and preventing ligand binding to the receptor complex. Follistatin has the ability to suppress the follicle stimulating hormone (FSH) [1][2]. Follistatin/FST Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 288 amino acids (G30-N317) .

Product Specifications

Product Name Alternative

Follistatin/FST Protein, Human (HEK293, His), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/follistatin-fst-protein-human-hek-293-his.html

Purity

98.0

Smiles

GNCWLRQAKNGRCQVLYKTELSKEECCSTGRLSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCN

Molecular Formula

10468 (Gene_ID) P19883-2 (G30-N317) (Accession)

Molecular Weight

Approximately 33-42 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

References & Citations

[1]Jakob Schiøler Hansen, et al. Circulating follistatin in relation to energy metabolism. Mol Cell Endocrinol. 2016 Sep 15;433:87-93.|[2]Ryan G Walker, et al. Heparin-mediated dimerization of follistatin. Exp Biol Med (Maywood) . 2021 Feb;246 (4) :467-482.|[3]D J Phillips, et al. Follistatin: a multifunctional regulatory protein. Front Neuroendocrinol. 1998 Oct;19 (4) :287-322.|[4]Jung-Chien Cheng, et al. FOXL2-induced follistatin attenuates activin A-stimulated cell proliferation in human granulosa cell tumors. Biochem Biophys Res Commun. 2014 Jan 10;443 (2) :537-42.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Storage Conditions

Stored at -20°C for 2 years

Scientific Category

Recombinant Proteins

Available Sizes

Frequently Asked Questions

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