SP3CHO
SP3CHO is an active metabolite generated by the metabolism of SP3N in cell culture by the action of amine oxidase. SP3CHO can induce polyubiquitination of specific proteins by recruiting the SCFFBXO22 E3 ligase complex. SP3CHO can be used in cancer therapy research[1].
Product Specifications
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sp3cho.html
Smiles
COC1=CC=C(CC[C@@H](OC([C@@H]2CCCCN2C(C(C(C)(C)CC)=O)=O)=O)C3=CC(NC(CCOCCOCCOCC=O)=O)=CC=C3)C=C1OC
Molecular Formula
C39H54N2O11
Molecular Weight
726.85
References & Citations
[1]Kagiou C, et al. Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation[J]. Nature Communications, 2024, 15 (1) : 5409.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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Reagecon Total Organic Carbon (TOC) Standard 10 mg/L (ppm)