Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

1-Dehydro-[10]-gingerdione

1-Dehydro-[10]-gingerdione directly inhibits IKKβ activity by targeting the activation loop of IKKβ, thus disrupting IKKβ-catalysed IκBα phosphorylation in macrophages stimulated with agonists. 1-Dehydro-[10]-gingerdione inhibits LPS (HY-D1056) -induced NF-κB transcriptional activity. 1-Dehydro-[10]-gingerdione has the potential for NF-κB-associated inflammation and autoimmune disorders research[1].

Product Specifications

CAS Number

[136826-50-1]

UNSPSC

12352005

Target

IKK; NF-κB

Type

Natural Products

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/1-dehydro-10-gingerdione.html

Solubility

10 mM in DMSO

Smiles

O=C(CC(CCCCCCCCC)=O)/C=C/C1=CC=C(C(OC)=C1)O

Molecular Formula

C21H30O4

Molecular Weight

346.46

References & Citations

[1]Hwa Young Lee, et al. 1-Dehydro-[10]-gingerdione from ginger inhibits IKKβ activity for NF-κB activation and suppresses NF-κB-regulated expression of inflammatory genes. Br J Pharmacol. 2012 Sep;167 (1) :128-40.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

SLC4A7 Antibody
MBS7127679-01 0.05 mL

SLC4A7 Antibody

Ask
View Details
SLC4A7 Antibody
MBS7127679-02 0.1 mL

SLC4A7 Antibody

Ask
View Details
SLC4A7 Antibody
MBS7127679-03 5x 0.1 mL

SLC4A7 Antibody

Ask
View Details
DNASE2 (Deoxyribonuclease-2-alpha, Acid DNase, DNase II, R31240_2, Deoxyribonuclease II alpha, DNASE2A, DNL2) (MaxLight 550)
125962-ML550 100 µL

DNASE2 (Deoxyribonuclease-2-alpha, Acid DNase, DNase II, R31240_2, Deoxyribonuclease II alpha, DNASE2A, DNL2) (MaxLight 550)

Ask
View Details
Rabbit anti-Escherichia coli (strain SMS-3-5/SECEC) DEOB Polyclonal Antibody
MBS7184669 Inquire

Rabbit anti-Escherichia coli (strain SMS-3-5/SECEC) DEOB Polyclonal Antibody

Ask
View Details
Recombinant Human Nucleoside diphosphate kinase 6 (NME6)
MBS1023007-01 0.02 mg (E-Coli)

Recombinant Human Nucleoside diphosphate kinase 6 (NME6)

Ask
View Details