Human CD1d Extracellular Domain/β2-Microglobulin Complex (recombinant)

<strong>Human CD1d Extracellular Domain/β2-Microglobulin Complex (recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2016784_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 100 µg_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Antigen-presenting Glycoprotein CD1d, B2M, β2-Microprotein, R3G1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Liu M, Chen HY, Luo L, Wang Y, Zhang D, Song N, Wang FB, Li Q, Zhang XL, Pan Q. Neutralization of IL-10 produced by B cells promotes protective immunity during persistent HCV infection in humanized mice Eur J Immunol. 2020 Sep;50(9):1350-1361._x000D_ 2: Ichimiya S, Kikuchi K, Matsuura A. Structural analysis of the rat homologue of CD1. Evidence for evolutionary conservation of the CD1D class and widespread transcription by rat cells J Immunol. 1994 Aug 1;153(3):1112-23._x000D_ 3: Kusaka H, Kita S, Tadokoro T, Yoshida K, Kasai Y, Niiyama H, Fujimoto Y, Hanashima S, Murata M, Sugiyama S, Ose T, Kuroki K, Maenaka K. Efficient preparation of human and mouse CD1d proteins using silkworm baculovirus expression system Protein Expr Purif. 2020 Aug;172:105631._x000D_ 4: Kim HS, Garcia J, Exley M, Johnson KW, Balk SP, Blumberg RS. Biochemical characterization of CD1d expression in the absence of beta2-microglobulin J Biol Chem. 1999 Apr 2;274(14):9289-95._x000D_ 5: Kunte A, Zhang W, Paduraru C, Veerapen N, Cox LR, Besra GS, Cresswell P. Endoplasmic reticulum glycoprotein quality control regulates CD1d assembly and CD1d-mediated antigen presentation J Biol Chem. 2013 Jun 7;288(23):16391-16402._x000D_ 6: Shrestha D, Exley MA, Vereb G, Szöllősi J, Jenei A. CD1d favors MHC neighborhood, GM1 ganglioside proximity and low detergent sensitive membrane regions on the surface of B lymphocytes Biochim Biophys Acta. 2014 Jan;1840(1):667-80._x000D_ 7: Chiu YH, Jayawardena J, Weiss A, Lee D, Park SH, Dautry-Varsat A, Bendelac A. Distinct subsets of CD1d-restricted T cells recognize self-antigens loaded in different cellular compartments J Exp Med. 1999 Jan 4;189(1):103-10._x000D_ 8: Dong Y, Lieskovska J, Kedrin D, Porcelli S, Mandelboim O, Bushkin Y. Soluble nonclassical HLA generated by the metalloproteinase pathway Hum Immunol. 2003 Aug;64(8):802-10._x000D_ 9: Braaten DC, McClellan JS, Messaoudi I, Tibbetts SA, McClellan KB, Nikolich-Zugich J, Virgin HW. Effective control of chronic gamma-herpesvirus infection by unconventional MHC Class Ia-independent CD8 T cells PLoS Pathog. 2006 May;2(5):e37._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/10570328">10: Housseau F, Bright RK, Simonis T, Nishimura MI, Topalian SL. Recognition of a shared human prostate cancer-associated antigen by nonclassical MHC-restricted CD8+ T cells J Immunol. 1999 Dec 1;163(11):6330-7.</a>_x000D_ _x000D_ <strong>Products Related to Human CD1d Extracellular Domain/β2-Microglobulin Complex (recombinant) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>