EZH2-IN-19
EZH2-IN-19 (conpound N40) is a potent inhibitor of enhancer of zeste homolog 2 (EZH2) WT, with the IC50 of 0.32 nM. EZH2-IN-19 plays an important role in cancer research[1].
Product Specifications
CAS Number
3026848-13-2
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ezh2-in-19.html
Smiles
CCN(C1CCC(CC1)N(C)C)C2=CC(C3=CC=C4C(N(C(N4C5CCN(C)CC5)=O)C)=C3)=CC(C(NCC6=C(C=C(NC6=O)C)C)=O)=C2C
Molecular Formula
C40H55N7O3
Molecular Weight
681.91
References & Citations
[1]Di Wu, et al. Discovery of novel pyridone-benzamide derivatives possessing a 1-methyl-2-benzimidazolinone moiety as potent EZH2 inhibitors for the treatment of B-cell lymphomas. Bioorg Med Chem. 2024 May 1:105:117725.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EZH2
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC217048L4 10 µg
TSH Receptor (TSHR) (NM_001018036) Human Tagged Lenti ORF Clone
Sign In for Pricing
View Details 
OR1064075-01 25 mg
2- (2- (2-Methoxyphenoxy) ethyl) isoindoline-1,3-dione
Sign In for Pricing
View Details OR1064075-02 50 mg
2- (2- (2-Methoxyphenoxy) ethyl) isoindoline-1,3-dione
Sign In for Pricing
View Details