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PS-915 (dihydrochloride)

PS-915 dihydrochloride is a peptide substrate used in a colorimetric assay for plasma antithrombin III (ATIII) . PS-915 dihydrochloride is highly specific for thrombin. By enzyme hydrolysis, PS-915 dihydrochloride liberates 3-carboxy-4-hydroxyaniline (CHA), which turns blue in color due to the complex formation with added alkaline-pentacyanoammine ferroate[1].

Product Specifications

CAS Number

86356-77-6

UNSPSC

12352005

Target

Thrombin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ps-915-dihydrochloride.html

Smiles

N=C(N)NCCC[C@@H](C(N)=O)N(C([C@H]1N(C([C@@H](CC2=CC=CC=C2)N)=O)CCC1)=O)C3=CC=C(O)C(C(O)=O)=C3.Cl.Cl

Molecular Formula

C27H37Cl2N7O6

Molecular Weight

626.53

References & Citations

[1]K Asai, et al. A colorimetric assay for plasma antithrombin III using a new synthetic peptide substrate (PS-915) . Clin Chim Acta. 1984 Dec 29;144 (2-3) :163-71.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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