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endo-BCN-PEG2-alcohol

Product Specifications

UNSPSC Description

endo-BCN-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-PEG2-alcohol is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Target Antigen

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/endo-bcn-peg2-alcohol.html

Solubility

10 mM in DMSO

Smiles

OCCOCCOCCNC(OCC1C2([H])C1([H])CCC#CCC2)=O

Molecular Weight

325.40

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-140076/endo-BCN-PEG2-alcohol-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-140076/endo-BCN-PEG2-alcohol-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1807501-85-4

Available Sizes

Curated Selection

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