Evifacotrep
Evifacotrep, a short transient receptor potential channel 5 and 4 (TRPC5/TRPC4) antagonist (WO2020061162, compound 100), can be used for the research of neurological diseases. Evifacotrep targets to TRPC5/TRPC4 with IC50s ≤50 nM[1].
Product Specifications
CAS Number
[2413739-88-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/evifacotrep.html
Purity
99.65
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1NN=CC(N2CC3=C(CC2)C(OC4=CC=C(C=C4C(F)(F)F)F)=NC=N3)=C1Cl
Molecular Formula
C18H12ClF4N5O2
Molecular Weight
441.77
Precautions
H302, H315, H319
References & Citations
[1]WO2020061162
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Mouse Endothelin Converting Enzyme 1 (ECE1) Antibody Pair Kit (with Standard)
Mouse Endothelin Converting Enzyme 1 (ECE1) Antibody Pair Kit (with Standard)
Mouse Endothelin Converting Enzyme 1 (ECE1) Antibody Pair Kit (with Standard)
Mouse Endothelin Converting Enzyme 1 (ECE1) Antibody Pair Kit (with Standard)