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(Z-LL) 2 ketone

(Z-LL) 2 ketone is an inhibitor of ketone with an IC50 value of 50 nM. (Z-LL) 2 ketone inhibits processing of thep-Prlsignal peptide[1].

Product Specifications

CAS Number

313664-40-3

UNSPSC

12352209

Target

Ser/Thr Protease

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/z-ll-2-ketone.html

Concentration

10mM

Purity

99.67

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OCC1=CC=CC=C1)N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(NCC(CNC([C@H](CC(C)C)NC([C@H](CC(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O)=O)=O)=O

Molecular Formula

C43H64N6O9

Molecular Weight

809.00

References & Citations

[1]A Weihofen, et al. Release of signal peptide fragments into the cytosol requires cleavage in the transmembrane region by a protease activity that is specifically blocked by a novel cysteine protease inhibitor. J Biol Chem. 2000 Oct 6;275 (40) :30951-6.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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