Losmapimod
Product Specifications
UNSPSC Description
Losmapimod (GSK-AHAB) is a selective, potent, and orally active p38 MAPK inhibitor with pKis of 8.1 and 7.6 for p38α and p38β, respectively[1].
Target Antigen
Autophagy; p38 MAPK
Type
Reference compound
Related Pathways
Autophagy;MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Losmapimod.html
Purity
99.96
Solubility
DMSO : 27.5 mg/mL (ultrasonic)|Ethanol : 33.33 mg/mL (ultrasonic)
Smiles
CC1=C(C2=NC=C(C(NCC(C)(C)C)=O)C=C2)C=C(C(NC3CC3)=O)C=C1F
Molecular Weight
383.46
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-10402/Losmapimod-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-10402/Losmapimod-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
585543-15-3
Available Sizes
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