GPR35 agonist 3

GPR35 agonist 3 is a synthetic GPR35 agonist with an EC50value of 1.4 μM. GPR35 agonist 3 can be used for the research of various diseases, such as gastric cancer, type 2 diabetes, cardiovascular diseases, immune system and peripheral nervous system[1].

Product Specifications

CAS Number

[123021-85-2]

UNSPSC

12352005

Hazard Statement

H319

Target

GPR35

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/gpr35-agonist-3.html

Purity

98.32

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(O)COC1=CC=C(/C=C(SC(N2)=O)\C2=O)C=C1

Molecular Formula

C12H9NO5S

Molecular Weight

279.27

Precautions

H319

References & Citations

[1]Dominik Thimm, et al. 6-Bromo-8- (4-[ (3) H]methoxybenzamido) -4-oxo-4H-chromene-2-carboxylic Acid: a powerful tool for studying orphan G protein-coupled receptor GPR35. J Med Chem