Difenoconazole-d6 (hydrochloride)

Difenoconazole-d6 (hydrochloride) is deuterium labeled Difenoconazole. Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth[1][2].

Product Specifications

CAS Number

[2748435-81-4]

UNSPSC

12352005

Target

Fungal; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

ClC1=CC=C(C=C1)OC2=CC(Cl)=C(C=C2)C3(OC([2H])(C([2H])(O3)[2H])C([2H])([2H])[2H])CN4C=NC=N4.Cl

Molecular Formula

C19H12D6Cl3N3O3

Molecular Weight

448.76

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Mu X, et al. Evaluation of acute and developmental effects of difenoconazole via multiple stage zebrafish assays. Environ Pollut. 2013 Apr;175:147-57.|[3]Dong F, et al. Chiral triazole fungicide difenoconazole: absolute stereochemistry, stereoselective bioactivity, aquatic toxicity, and environmental behavior in vegetables and soil. Environ Sci Technol. 2013 Apr 2;47 (7) :3386-94.