Difenoconazole-d6 (hydrochloride)
Product Specifications
UNSPSC Description
Difenoconazole-d6 (hydrochloride) is deuterium labeled Difenoconazole. Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth[1][2].
Target Antigen
Fungal; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection;Others
Field of Research
Infection
Smiles
ClC1=CC=C(C=C1)OC2=CC(Cl)=C(C=C2)C3(OC([2H])(C([2H])(O3)[2H])C([2H])([2H])[2H])CN4C=NC=N4.Cl
Molecular Weight
448.76
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Mu X, et al. Evaluation of acute and developmental effects of difenoconazole via multiple stage zebrafish assays. Environ Pollut. 2013 Apr;175:147-57.|[3]Dong F, et al. Chiral triazole fungicide difenoconazole: absolute stereochemistry, stereoselective bioactivity, aquatic toxicity, and environmental behavior in vegetables and soil. Environ Sci Technol. 2013 Apr 2;47(7):3386-94.
Shipping Conditions
Room temperature
Clinical Information
Phase 3
CAS Number
2748435-81-4
Curated Selection
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