C-Met inhibitor 1
C-Met inhibitor 1 is an orally active c-Met inhibitor. c-Met inhibitor 1 can inhibit c-Met phosphorylation with an IC50 of 0.010 μM. c-Met inhibitor 1 has antitumor activity and can be used for the research of tumors such as gastric cancer, pancreatic cancer and malignant glioma[1].
Product Specifications
CAS Number
[1357072-61-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
C-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c-Met-inhibitor-1.html
Concentration
10mM
Purity
98.89
Solubility
DMSO : 20 mg/mL (ultrasonic)
Smiles
CN1N=CC(C2=NN3C(C=C2)=NN=C3SC4=CC5=CN(C)N=C5C=C4)=C1
Molecular Formula
C17H14N8S
Molecular Weight
362.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhipei Wu. 6- (1-methyl-1h-pyrazol-4-yl) -3- (2-methyl-2h-indazol-5-. WO2012015677A1. 2012-02-02.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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