BaENR-IN-1

BaENR-IN-1 (Compound 5) is an inhibitor of Enoyl-Acyl Carrier Protein Reductase (ENR) (IC50= 7.7 μM) . BaENR-IN-1 blocks the synthesis of fatty acids essential for bacterial growth by inhibiting the bacterial enzyme ENR. BaENR-IN-1 shows activity against bacteria[1].

Product Specifications

CAS Number

[1071966-17-0]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/baenr-in-1.html

Solubility

10 mM in DMSO

Smiles

O=[N+]([O-])C1=CC=CC=C1OC2=C(O)C=C(Cl)C=C2

Molecular Formula

C12H8ClNO4

Molecular Weight

265.65

References & Citations

[1]Suresh K Tipparaju, et al. Design and synthesis of aryl ether inhibitors of the Bacillus anthracis enoyl-ACP reductase. ChemMedChem. 2008 Aug;3 (8) :1250-68.