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Peimisine (hydrochloride)

Peimisine (Ebeiensine) hydrochloride is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine hydrochloride shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research[1][2][3].

Product Specifications

CAS Number

900498-44-4

Product Name Alternative

Ebeiensine (hydrochloride)

UNSPSC

12352005

Target

Angiotensin-converting Enzyme (ACE) ; Apoptosis; mAChR

Type

Natural Products

Related Pathways

Apoptosis; GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/peimisine-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

CC1=C(C[C@@]2([H])[C@@]3([H])CC([C@]4([H])[C@@]2(CC[C@@H](C4)O)C)=O)[C@@]3([H])CC[C@]15O[C@@]6([H])[C@](NC[C@H](C6)C)([H])[C@H]5C.[H]Cl

Molecular Formula

C27H42ClNO3

Molecular Weight

464.08

References & Citations

[1]Pan F, et al. Peimisine and peiminine production by endophytic fungus Fusarium sp. isolated from Fritillaria unibracteata var. wabensis. Phytomedicine. 2014 Jul-Aug;21 (8-9) :1104-9.|[2]Armando Alberola-Die, et al. Peimine, an Anti-Inflammatory Compound from Chinese Herbal Extracts, Modulates Muscle-Type Nicotinic Receptors. Int J Mol Sci. 2021 Oct 19;22 (20) :11287.|[3]Dongdong Wang, et al. Evaluation of antitumor property of extracts and steroidal alkaloids from the cultivated Bulbus Fritillariae ussuriensis and preliminary investigation of its mechanism of action. BMC Complement Altern Med. 2015 Feb 21;15:29.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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