Benzoquinoquinoxaline
Benzoquinoquinoxaline (BQQ) is a heterocyclic compound with an aminoalkyl side chain. Benzoquinoquinoxaline preferentially binds to DNA triplex structures, intercalates between the bases, thus, stabilising the triplex conformation. Conjugation of Benzoquinoquinoxaline to 1,10-phenanthroline specifically binds and cleaves double strand DNA at the site of formation of a triplex structure[1].
Product Specifications
CAS Number
207671-99-6
Product Name Alternative
BQQ
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/benzoquinoquinoxaline.html
Purity
99.68
Solubility
DMSO : 130 mg/mL (ultrasonic)
Smiles
NCCCNC1=NC2=C(C3=C1N=C(C=CC4=C5C=CC(OC)=C4)C5=N3)C=CC=C2
Molecular Formula
C23H21N5O
Molecular Weight
383.45
References & Citations
[1]Umek T, et al. Oligonucleotide Binding to Non-B-DNA in MYC. Molecules. 2019 Mar 12;24 (5) :1000.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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