Sandoz 58-035
Sandoz 58-035 is a competitive inhibitor of cholesterol acyltransferase (ACAT) . Sandoz 58-035 effectively inhibits (>98%) hormonally stimulated cholesterol esterification in cells[1].
Product Specifications
CAS Number
78934-83-5
UNSPSC
12352005
Target
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/sandoz-58-035.html
Purity
99.35
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC(C1=CC=CC=C1)CC2=CC=C(C)C=C2)CC[Si](C)(CCCCCCCCCC)C
Molecular Formula
C30H47NOSi
Molecular Weight
465.79
References & Citations
[1]Veldhuis JD, et al. The role of cholesterol esterification in ovarian steroidogenesis: studies in cultured swine granulosa cells using a novel inhibitor of acyl coenzyme A: cholesterol acyltransferase. Endocrinology. 1985;116 (1) :25-30.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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