EGFR-TK-IN-2
EGFR-TK-IN-2 (compound 10b) is EGFR-TK inhibitor with the IC50 of 0.16 μM. EGFR-TK-IN-2 inhibits cell growth[1].
Product Specifications
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antiproliferative-agent-50.html
Solubility
10 mM in DMSO
Smiles
O=[N+](C1=CC(C2CC(C3=CC=C(OCC4=CC=CC=C4)C=C3)=NN2)=CC=C1)[O-]
Molecular Formula
C22H19N3O3
Molecular Weight
373.40
References & Citations
[1]Serag MI, et al. M. New oxadiazole and pyrazoline derivatives as anti-proliferative agents targeting EGFR-TK: design, synthesis, biological evaluation and molecular docking study. Sci Rep. 2024;14 (1) :5474. Published 2024 Mar 5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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