DLC27-14

DLC27-14 is a HIV Nef inhibitor with the IC50 of 15.92 μM. DLC27-14 can be used for study of HIV-1[1][2].

Product Specifications

CAS Number

[1360869-92-6]

UNSPSC

12352005

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dlc27-14.html

Smiles

O=C(C1=CC(NC(COC2=CC=C(C3=CC=C(C(C)(C)C)C=C3)C=C2)=O)=CC=C1)O

Molecular Formula

C25H25NO4

Molecular Weight

403.47

References & Citations

[1]Lugari A, et al. A specific protein disorder catalyzer of HIV-1 Nef. Bioorg Med Chem. 2011;19 (24) :7401-7406. |[2]Trible RP, et al. Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef function using a yeast-based phenotypic screen. Retrovirology. 2013;10:135. Published 2013 Nov 14.