LC3in-C42
LC3in-C42 is a cell-active LC3A/B and autophagy covalent inhibitor. LC3in-C42 selectively inhibits the binding of P62 to LC3A/B in vitro and at the cellular level like D5 and can function on a lower concentration[1].
Product Specifications
UNSPSC
12352005
Target
Autophagy; p62
Type
Reference compound
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lc3in-c42.html
Smiles
O=C1/C(C(CC(C1)C2=C(C(Cl)=CC3=C2C=CN3)Cl)=O)=C/NCCN(C)C
Molecular Formula
C19H21Cl2N3O2
Molecular Weight
394.29
References & Citations
[1]Zhenfei Zhou, et al. Structure-Based Design and Discovery of a Potent and Cell-Active LC3A/B Covalent Inhibitor. J Med Chem. 2024 Jul 25;67 (14) :12184-12204.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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