Atropine methyl (nitrate)

Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist, is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine[1][2].

Product Specifications

CAS Number

[52-88-0]

Product Name Alternative

Methylatropine (nitrate) ; Atropine methyl nitrate

UNSPSC

12352005

Hazard Statement

H300+H330

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/atropine-methyl-nitrate.html

Purity

99.2

Smiles

[O-][N+]([O-])=O.C[N+]1([C@H]2C[C@H](OC(C(C3=CC=CC=C3)CO)=O)C[C@@H]1CC2)C

Molecular Formula

C18H26N2O6

Molecular Weight

366.41

Precautions

H300+H330

References & Citations

[1]Methylatropine.|[2]Nurminen ML, et al. Central inhibition of nitric oxide synthesis increases blood pressure and heart rate in anesthetized rats. Methods Find Exp Clin Pharmacol. 1997 Jan-Feb;19 (1) :35-41.